The Effects of Prolactin-Raising and Prolactin-Sparing Antipsychotics on Prolactin Levels and Bone Mineral Density in Schizophrenic Patients Şizofreni Tanılı Hastalarda Prolaktini Yükselten ve Az Etkileyen Antipsikotiklerin Prolaktin Seviyesi ve Kemik Mineral Yoğunluğu Üzerine Etkileri
نویسندگان
چکیده
Süheyla DOĞAN BULUT1, Serdar BULUT2, Verda TÜZER3, Mehmet AK4, Emine AK5, Cebrail KISA3, Çiğdem AYDEMİR3, Erol GÖKA6 1Clinic of Psychiatry, Gazi Mustafa Kemal State Hospital, Ankara, Turkey 2Clinic of Psychiatry, Etimesgut Military Hospital, Ankara, Turkey 3Clinic of Psychiatry, Ankara Numune Training and Research Hospital, Ankara, Turkey 4Clinic of Psychiatry, Gülhane Military Medical Academy, Ankara, Turkey 5Clinic of Psychiatry, Kilis State Hospital, Kilis, Turkey 6Department of Psychiatry, Konya Selçuk University, Meram Faculty of Medicine, Konya, Turkey
منابع مشابه
Comparison of short term effects of risperidone and paliperidone on serum prolactin levels in female patients
Amaç: Hiperprolaktinemi antipsikotik kullanımı ile ilişkili bir yan etkidir. Tüm tipik antipsikotiklerin serum prolaktin düzeylerini yükselttiği kabul edilmektedir. Tipik antipsikotiklerle karşılaştırıldığında, atipik antipsikotiklerin serum prolaktin düzeylerini yükseltmeleri açısından daha düşük eğilimleri vardır. Ancak tüm atipik antipsikotiklerin serum prolaktin düzeyi üzerine etkileri her ...
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BACKGROUND The aim of this study was to compare the bone mineral density (BMD) of male schizophrenia patients with those of healthy controls in order to determine the relationship between BMD and hormonal changes. SUBJECTS AND METHODS The study sample included male outpatients between 18 and 55 years old, diagnosed with schizophrenia who had used prolactin-raising antipsychotics (n=23) and pr...
متن کاملEffects of Antipsychotics on Bone Mineral Density in Patients with Schizophrenia: Gender Differences
Low bone mineral density (BMD) and osteoporosis are common in patients with schizophrenia and detrimental to illness prognosis and life quality. Although the pathogenesis is not fully clear, series of studies have revealed factors related to low BMD such as life style, psychotic symptoms, medication use and the activity of bone absorption markers. It has been known that antipsychotic-induced hy...
متن کاملRisk of hip fracture in patients with a history of schizophrenia.
BACKGROUND There is evidence of an association between decreased bone mineral density, schizophrenia, and prolactin-raising antipsychotic medication. However, it is not known whether this is clinically significant. AIMS To investigate whether patients with a history of schizophrenia are at increased risk of hip fracture. METHOD In a case-control study, we compared cases of 'hip fracture' on...
متن کاملEffects of elevated serum prolactin on bone mineral density and bone metabolism in female patients with schizophrenia: a prospective study.
OBJECTIVE This study was designed to prospectively examine differential effects of sustained "high" and "low" serum prolactin levels on bone mineral density and peripheral markers of bone metabolism. METHOD A dual-energy X-ray absorptiometer was used to measure bone mineral density. Peripheral markers of bone formation and resorption were used to measure bone metabolism in 14 Caucasian female...
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